CPSA Metabolomics 2019

Meeting Program

Updated April 3, 2019

Monday March 11  Pre-Conference Workshop

1:00 pm - 4:00 pm



Actionable Sustainability - Getting Ahead of The Curve for Early Diagnosis of Preventable Diseases

Jeremiah Tipton, BioTech & OMICSx Solutions, LLC

Quick Overview of Cutting Edge OMICS Technologies and Diagnostic Assays

Defining Success in the Promise of OMICS to Diagnostics: Personalize/Precision Medicine

5:00 pm - 7:00 pm


Welcome Reception & Metabolomics Lecture Series

Metabolics Lecturer Carla Cuthbert

Targeted Metabolomics for Disease Detection in Newborn Screening: Addressing Future Possibilities and Challenges

Carla Cuthbert
Centers for Disease Control & Prevention

Tuesday March 12

7:30 am - 8:30 am


Good Morning

Registration & Coffee

8:30 AM - 9:00 AM


Welcome & Opening Remarks

Mike Lee

Mike Lee
Milestone Development Services

Abhishek Jha

Format, Objectives, Opening Remarks
Abhishek Jha

Andrew Lee

Andrew Lee

9:00 AM - 9:45 am


Plenary Lecture

Plenary Speaker

Bench to Bedside: Making a Difference in Quality of Life One Drop at a Time

Athena Zuppa
The Children's Hospital of Philadelphia

10:00 am - 11:30 am


Symposium Session

New Technology, Metabolism & Rare Disease

Discussion Leader: Andrew Lee, IMCS

Cystic Fibrosis Metabolomics
Facundo Fernandez, Georgia Institute of Technology

Fumarate Excess Exacerbates Mitochondrial Functional Deficits During Mitochondrial Disease
Norma Frizzell, University of South Carolina

More Accurate Analysis of Beta-Agonists in Urine and Tissue Samples: The Impact of Clean and Efficient Sulfatase and Beta-Glucuronidase in Metabolites Analysis
Qian Wang, University of South Carolina

11:45 am - 1:15 pm



QA/QC for Standardization in Metabolomics – Analytical Rigor in Untargeted Discovery and Routine Analysis Alike

An interactive dialog with panelists and audience members about QA/QC and how this is best applied to LC-MS analysis for untargeted metabolomics but also routine analysis such as large scale clinical cohorts.

Panel Discussion
Discussion Leader: Amanda Souza, Thermo Fisher Scientific

Chris Beecher, IROA Technologies, LLC
Annie Evans, Metabolon
David Gaul, Georgia Institute of Technology
Ken Liu, Emory University
Konstantinos Petritis, Centers for Disease Control and Prevention
Hubert Vesper, Centers for Disease Control and Prevention

1:30 pm - 3:00 pm


Symposium Session

Harmonization & Standardization in the Clinical Lab

Discussion Leader: Suzanne Cordovado, Centers for Disease Control & Prevention; Emily Ehrenfeld, New Objective

State of Harmonization in the Clinical Laboratory: Benchmarks and Where We Need to Be
Lorin Bachmann, VCU Health System

Tenofovir Urine Assay to Monitor Adherence to HIV Pre-Exposure Prophylaxis
Ganesh Moorthy, The Children's Hosital of Philadelphia

CDC's Clinical Standardization Programs: Supporting Clinical Laboratories to Harmonize and Standardize Clinical Tests
Hubert Vesper, Centers for Disease Control & Prevention

3:15 pm - 4:45 pm


Symposium Session

Harmonization & Standardization in the Pre-Clinical Lab

Discussion Leader: Abhishek Jha and Shefali Lathwal, Elucidata

Industrializing Flux Capabilities
Darren Dumlao, SCIEX

Suppression Correction using Complex Isotopic Internal Standards
Chris Beecher, IROA

Polly as an Multi-Omics platform
Abhishek Jha, Elucidata

Wednesday March 13

7:30 am - 8:30 am


Good Morning

Registration & Coffee

8:30 am - 10:00 am



Discussion Leader: Lorin Bachmann, VCU Health System; Mike Lee, Milestone Development Services

10:15 am - 11:45 am


Symposium Session

Emerging Technologies and Methods: Omics to Bedside

Discussion Leader: Jeremiah Tipton, BioTech & OMICSx Solutions, LLC

Preoperative Metabolomic Signature of Prostate Cancer Recurrence
David Gaul, Georgia Institute of Technology

Deep Metabolomics of an Ovarian Cancer Triple Knockout Mouse Model
Danning Huang, Georgia Institute of Technology

Finding Success in the Current State of Translating OMICS to Bedside
Jeremiah Tipton, BioTech & OMICSx Solutions, LLC

Panel Discussion

12:00 pm - 1:30 pm


Sponsored Lunch & Vendor Spotlight

Accelerating Metabolomics with New Innovations from Agilent

John Sausen, Agilent Technologies

Agilent continues to innovate solutions to address the challenges of metabolic research. This workshop will introduce the latest developments from Agilent for metabolomics. Starting with sample preparation, the new Agilent Metabolomics Workbench provides semi-automated preparation of plasma samples including room temperature quenching and removal of lipids. In addition, a new LC/Q-TOF platform will be presented that simultaneously combines the speed, sensitivity, resolution, dynamic range, and isotopic fidelity needed to accelerate metabolomics research. Finally, the latest software enhancements for lipid annotation and automated data analysis will be discussed. Join us to hear more about these exciting new additions to our comprehensive portfolio.

1:30 pm - 3:00 pm


Vendor Session

Vendors Meet Customers

Discussion Leaders: Alla Kloss, Sanofi; Jeremiah Tipton, BioTech & OMICSx Solutions, LLC

Re-Inventing the Metabolomics Untargeted Workflow with the Thermo Scientific Orbitrap ID-X Tribrid MS
Amanda Souza
Metabolomics Program Manager, Thermo Fisher Scientific

Plug & Play Targeted Methods and Kits-A Step Towards Standardization
Hernando Olivos
Principal Applications Scientist, Waters Corporation

Integrated Solutions for NanoFlow and MicroFlow LC-MS:
A Vision for a Validated CPU
Emily Ehrenfeld
CEO, New Objective

3:15 pm



Closing Remarks

Abhishek Jha, Elucidata
Andrew Lee, IMCS
Mike Lee, Milestone Development Services